Why Is One Knee Swollen but Not the Other?

Sudden knee swelling can be caused by inflammatory conditions like gout or pseudogout, which bring “intense pain and stiffness.” Though arthritis usually affects both knees, it may appear in just one, especially after injury or overuse. Tendonitis can also cause swelling under similar circumstances.

A serious concern is septic arthritis, an infection that results in “sudden, severe swelling” and needs emergency care. Warning signs include fever, extreme pain, or redness—seek help immediately if these occur.

For milder cases, the RICE method—Rest, Ice, Compression, Elevation—can ease symptoms. Over-the-counter anti-inflammatory medications may also help.

Still, if symptoms persist or worsen, it’s important to see a healthcare provider to get the correct diagnosis and avoid long-term damage. As the article notes, “early intervention often leads to better outcomes.”

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