Various factors such as trauma, infection, skin issues, and pressure on the feet can lead to changes in the skin, including the toes and heels. Corns and calluses result from friction and pressure, while juvenile plantar dermatosis affects children’s feet. Foot infections encompass warts, athlete’s foot (caused by a fungus thriving in warm, humid conditions), and bacterial infections like pitted keratolysis. Hand-foot-and-mouth disease causes blisters on the feet, palms, and mouth. Toenail fungus details can be found on our Nails information page. Skin diseases affecting the foot include dyshidrotic eczema, marked by itchy blisters on the palms, fingers, instep, or toes. Gout, a form of arthritis, commonly targets the big toe joint, causing acute pain and swelling. Visit our information page for self-care tips and images of foot fungus, infections, and injuries.